Country websites:


The medical device and therapy related information on this website is aimed exclusively at healthcare professionals.

Not all products are cleared or available for sale in all Asia Pacific countries.

By clicking on the button "Accepted and Confirmed" you assure that you have taken note of this information and that you are a healthcare professional.

FX CorDiax

FX CorDiax 100

Designed to dialyze.
Built for cardioprotection.

  • Efficient middle molecule removal
  • INLINE steam sterilized
  • Lowest albumin loss
  • Low rinsing volume

Key features

High selective permeability for middle molecules

The new FX CorDiax is the most efficient dialyzer within the FX-class®. The core of the FX CorDiax is the Helixone® plus membrane, a targeted enhancement of the Helixone® membrane. Improved fiber design allows for better sieving of middle molecules such as β2-microglobulin (β2-m) while restricting the loss of vital albumin. As increased levels of β2-m are associated with higher mortality risk, the use of FX CorDiax High-Flux dialyzers or hemodiafilters facilitate best possible therapy outcomes.

Refined membrane architecture

New production technology combined with INLINE steam sterilization allows crucial enhancements of membrane porosity, reducing flow resistance and improving transport across the membrane.

The Helixone®plus membrane
Close-up of the inner surface and the support region of the Helixone®plus membrane

Benefit of refined membrane architecture

Significantly improved removal of middle molecules while preventing the loss of useful substances, such as serum albumin.

Purity enhanced — with steam


Advances in fiber design allow for better removal of uremic toxins

Superior by design

Several state-of-the-art technologies have been combined to create the distinctive, functional features of FX-class® dialyzers, which are refined and optimized for performance and handling:

  • Design of dialyzer housing and fiber bundle for more uniform dialysate flow
  • Refined blood inlet port for improved hemodynamics  

Advances in material and production technologies have permitted improvements in the wall structure of the Helixone®plus membrane of the FX CorDiax.  

  • More porous membrane wall for higher clearance of middle molecules
Optimized dialysate flowThe 3-dimensional microwave structure of the fiber ensures uniform radial dialysate flow around each fiber within the bundle by preventing fluid channeling, thereby enhancing clearance values and improving the overall performance of the dialyzer.  
Better hemodynamicsThe lateral blood-inlet port ensures more homogenous blood flow in the dialyzer header, preventing stagnation zones. The design essentially minimizes the risk of kinking, contributing to improved safety.
Enhanced convectionThe more open structure of the Helixone®plus membrane support region serves to reduce diffusion resistance and increases convective filtration. This facilitates clearance of a broad range of uremic toxins, especially the middle molecules.
Kind to the environmentAdvanced design goes beyond direct functionality, it also has to be easy on the environment. FX-class® dialyzers weigh half as much as dialyzers with polycarbonate housing, and at the same time use ecologically friendly plastics. This means a lower carbon-footprint as a result of fewer materials, less packaging, less fuel for transport and cleaner waste management.
FX-class® dialyzers design
FX-class® dialyzers design

Key to optimal middle molecule removal

Fiber design for HD

Design of the HD fiber

  • A small inner diameter of the hollow fiber increases the pressure gradient between blood and dialysate compartments
  • The result is improved clearance of middle molecules such as vitamin B12, inulin, β2-microglobulin and myoglobin1  
  • The increased pressure gradient combined with structural refinements to the membrane (support region) enhances diffusive as well as convective filtration, especially when performing High-Flux hemodialysis with FX CorDiax

FX CorDiax hemodiafilter

Increased fiber lumen for better flow conditions

  • An increase of its inner diameter results in a reduced pressure drop within a hollow fiber
  • The  capillary diameter of a dialyzer can affect performance and treatment quality
  • The inner diameter of hemodiafilters is 210 μm compared to 185 μm of HD filters. The larger diameter facilitates improved flow conditions, allowing for higher convective volumes in an HDF treatment2

Performance Data

Sieving coefficients of FX CorDiax High-Flux Dialyzers and Haemodiafilters

FX CorDiax High-Flux Dialysers

FX CorDiax Haemodiafilters


“… treating patients with online hemodiafiltration and FX CorDiax 60 instead of FX 60 dialyzers results in significantly increased reduction ratios of middle sized molecules without clinically relevant changes in albumin loss.”

Maduell et. al.

In a postdilution HDF treatment the use of FX CorDiax 100 dialyzers resulted in a significantly higher clearance of β2-microglobulin than FX 100 and Polyflux® 210H dialyzers. The albumin loss was low and similar for all dialysers.4

Comparison of albumin loss in a post-dilution HDF treatment

(QB = 350 mL/min, QD = 800 mL/min, QS = 80 mL/min)4

Related content

1 Dellanna F. et al., (1996); Nephrology Dialysis Transplantation 11 (Suppl 2): 83-86.

2 Vega Vega O.; ERA-EDTA Congress 2012, Poster 457—FP.

3 Maduell et. al.; ERA-EDTA Congress 2013, May 20, Poster Number MP 390.

4 Bock A. et al., Journal of the American Society of Nephrology (2013); 24: SA-PO404.