Designed to dialyze, built for cardioprotection
The FX CorDiax dialyzers feature the advanced Helixone® plus membrane, enabling the enhanced removal of larger uremic toxins, such as β2-microglobulin and myoglobin.2,3 At the same time, it restricts the loss of albumin, which is of clinical concern and a safety issue in hemodialysis.4
FX CorDiax high-flux dialyzers or hemodiafilters facilitate beneficial therapy outcomes.
High-flux dialyzers for improved patient outcomes
The FX classix dialyzers, featuring the original Helixone® membrane, target at an efficient removal of a broad range of uraemic toxins with high endotoxin retention characteristics.5,6
FX classix dialyzers provide high-flux hemodialysis therapy to improve clinical outcomes in patients in comparison to low-flux hemodialysis.7
High-flux dialyzer for paediatric treatments
The FX paed dialyzer enables high-flux hemodialysis therapy ideally suited for the special needs of pediatric patients. It features the original Helixone® membrane, which targets at an efficient removal of a broad range of uremic toxins, with minimum albumin losses and high endotoxin-retaining characteristics.8
Advanced design for low-flux dialysis
The removal of uremic toxins and excessive water is the fundamental goal of the hemodialysis treatment. Due to the beneficial properties of the Helixone® low-flux membrane combined with its advanced product design, the FX low-flux dialyzers offer adequate performance.9
“Flow 1”, acrylic on canvas
The theme is the continuous flow of blood and life. The blue strap in the middle represents the uniform flow of blood and a continuously calm treatment. Dialysis is a life-giving stream that runs through the lives of those it affects. The abstract language of the form invites various interpretations.
“Running Waves”, acrylic
Emotions are in focus – this image should relax and convey peace. A combination of a variety of used cardboards and flowing blue tones. The image shows calmly lapping waves, symbolizing the microwave structure of the fibers.
“Flying Caps”, photography
The lightness and sustainability of the material is represented by floating caps, which were captured with a special lens that gives the image a feeling of immediate airiness and clarity.
“Dynamic Spiral”, pouring technique
This image is about the radial distribution of blood in the dialyzer. With the pouring technique, colors are poured onto the undercoat and distributed over the surface by a swinging motion. The speed and dynamic of the flowing blood are at the center of this concept.
“Endless”, digital reproduction
A constantly repetitive process results in infinity. This shows the breadth and variety of possibilities that can arise from a single object – as demonstrated in the diverse FX dialyzers portfolio.
1 Wagner S. et al., Nephrology Dialysis Transplantation (2017); 32 (3): iii615.
2 Bock A. et al., J Am Soc Nephrol (2013); 24: SA-PO404.
3 Maduell F. et al., Blood Purif. (2014); 37(2): 125-130.
4 Lim P. S. et al., Artif Organs (2017); Nov 27. doi: 10.1111/aor.13011.
5 Schindler R. et al., Clin. Nephrology (2003); 59: 447–454.
6 Weber V. et al., Artif Organs (2004); 28(2): 210-217.
7 Chazot C. et al., Nephron (2015); 129: 269-275.
8 Tsai I.J. et al., Pediatr Nephrol (2014); 29: 111–116.
9 Data from Fresenius Medical Care Deutschland GmbH: Comparison clearance values F8 HPS (effective surface area 1.8 m2) versus FX 8 (effective surface area 1.4 m2).
10 Ronco C., Nissenson A. R., Blood Purif (2001); 19: 347-352.
11 Ronco C. et al., Kidney International (2002); 61 (80): 126-142.
12 Külz M. et al., Nephrol Dial Transplant (2002); 17: 1475-1479.
13 Mandolfo S. et al., The International Journal of Artificial Organs (2003); 26 (2): 113-120.
14 Allard B. et al., Le Pharmacien Hospitalier et Clinicien (2013); 48 (4): 15-21.
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16 Hirata N. et al., Radiation Physics and Chemistry (1995); 46 (3): 377–381.
17 Golli-Bennour E. E. et al., International urology and nephrology (2011); 43 (2): 483–490.
18 Azzabi A. et al., Néphrologie & Thérapeutique (2014); 10 (5): 318.
19 Golli-Bennour E.E et al., World J Nephrol Urol (2017); 6 (1-2): 14-17.
20 da Silva Aquino K. A., INtechOpen (2012); www.intechopen.com/books/gamma-radiation/sterilization-by-gamma-irradiation (27.04.2018).
21 Dawids S., Handlos V. N., Developments in hematology and immunology (1989); 347–368.
22 Unpublished data from Fresenius Medical Care Deutschland GmbH: Internal calculation based on weight measurements before treatment of FX Dialysers versus F-series dialysers.
23 Unpublished data from Fresenius Medical Care Deutschland GmbH: Internal calculation based on weight measurements of FME FX classix 80 versus FME HF 80S. The typical number of treatments in most clinics is approximately 10,000 per year; this results in about 1,600 kg less waste being produced annually with FX classix 80 when used on FME 5008 CorDiax machine.
24 EC-JRC-IES (2011): ILCD handbook – Recommendations for LCIA in the European context. Source: publications.jrc.ec.europa.eu/repository/handle/JRC61049 (all 15 environmental impact categories with recommendation in table 1 of this ILCD handbook have been evaluated).
25 Unpublished data from Fresenius Medical Care Deutschland GmbH internal study (2018): Comparative life cycle assessment of selected FME dialysers. Eco-performance is always calculated versus baseline product (FME HF 80S); long distance scenario illustrated.