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Continuous renal replacement therapy (CRRT) set-ups

CRRT set-ups

Different options as standard therapies for acute kidney injury

  • Continuous Veno-Venous Hemodialysis (CVVHD)
  • Continuous Veno-Venous Hemofiltration (CVVH)
  • Continuous Veno-Venous Hemodiafiltration (CVVHDF)

CRRT at a glance

post-dilution CVVHDF
  • CVVHD and post CVVHDF enable efficient use of CRRT-fluid. Any predilution would dilute uremic toxins and reduce efficacy of CRRT-fluid usage.
  • Minimal or limited hemoconcentration with CVVHD and post

multiFiltrate Ci-Ca® EMiC®2

When Ci-Ca® and EMiC®2 are combined the patient benefits from an established Ci-Ca CVVHD protocol as well as an increased middle-molecule clearance.

For more details see:

EMiC®2 filter 

Continuous Veno-Venous Hemodialysis (CVVHD)

Continuous Veno-Venous Hemodialysis (CVVHD)
Continuous Veno-Venous Hemodialysis (CVVHD)

CVVHD is a diffusion based therapy. Blood is pumped through the blood compartment of the filter and dialysate flows counter-currently. The counter-current flow optimizes the diffusion gradient and, thus the resulting clearances. Practically with CVVHD, dialysate flow is clearly smaller than the blood flow, corresponding to clearances closely related to dialysate flow.

Continuous Veno-Venous Hemofiltration (CVVH)

Continuous Veno-Venous Hemodiafiltration (CVVHDF)

CRRT vs. iHD

Renal replacement therapy (RRT) for the treatment of acute kidney injury (AKI) is mostly realized as extracorporeal blood purification.

Among the extracorporeal blood purification methods, mainly CRRT and intermittent hemodialysis (iHD) are used to treat AKI. Intermittent hemodialysis means application of RRT as it is otherwise applied in chronic dialysis patients with treatment duration of, e.g., 4 hours.

SLEDD

The advantages of CRRT and iHD

Content Related

1 Bell M et al., Intensive Care Medicine (2007); 33: 773-780

2 Uchino et al, The International journal of Artificial Organs (2007); 30: 281-292

3 Lin YF et al, The American Journal of Surgery (2009); 198: 325-332

4 Schneider AG et al., Intensive Care Medicine (2013); 39: 987-997

5 Wald R et al., Critical Care Medicine (2014); 42: 868-876

6 Bellomo R & Schneider AG, Critical Care Medicine (2014); 42: 990-991